It is my understanding that states set minimum standards and every municipality has the right to increase, but not decrease, those restrictions. Every county wher I live and do business is different. We have some that are the highest... the same as FDA standards, and we have a neighboring county where I wouldn't dare eat, their restrictions are so lax.
No CFL will over-ride zoning. Full licenses can't over-ride that either. the first thing I had to do was to get a zoning sign-off. All businesses go through this. Even a CPA who works from home may need a zoning variance.