My nephew is turning 1 and they want to do Jesus loves the little chidlren theme.. I am BLANK on what kind of cake to make? Any suggestions from anyone would be awesome!

the first thing that popped into my mind is "red and yellow, black and white" so maybe you could use those colors in some way? Not sure what size cake you have in mind, or if you're looking at a sheet cake, stacked cake, etc. But those colors could either be incorporated as little people, either molded or cut out of fondant like say with a gingerbread man cookie cutter. The colorful people can encircle the whole cake like they are linked by their hands. Maybe a heart on top of the cake? I guess a lot depends on the type and size of the cake.
HTH,
Crissy